There is no definitive answer to this question since the name of a registry entry can change for any number of reasons. However, one possible way to find a registry entry with a changing name is to use a registry editor tool to search for all entries that have been modified within a certain time...
Django is a good fit for larger projects and is very mature framework to work with, i have used this on many client projects and does work well, I see flask as a minimal framework to launch ideas up quickly
Django does have a bit of a learning curve but it is very flexible to meet many needs...
I have used Tailwind myself its not that hard to use or learn and is a great to work with. The only drawback is they do charge a price for extras, though my personal preference is Bootstrap as there are more resources around the web for it.